Human papilomavirus and vaccinessteemCreated with Sketch.

in #science7 years ago (edited)

Versión en español: https://steemit.com/spanish/@ropaga/virus-del-papiloma-humano-y-vacunas

Human papilomavirus (HPV)is a group of more than 200 sexual transmission virus, some of them can cause genital and throat warts and some types of cancer ( neck uterus, anus, mouth, throat, vulva, vagina, penis, tongue, tonsils) The main cause of cancer are types 16 and 18, followed by types 31, 33, 45, 52 and 58. The main cause of warts are types 6 y 11.

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HPV is the most common sexual transimission infection, in the USA about 40% of population under 60 years is infected. Besides the use of condom greatly reduces the risk of infection it does not completely prevent it, because it can also be transmited through skin-skin contact, especially with warts. In the USA between 2009 and 2013 HPV caused 23 300 cancer cases in women and 16 500 cancer cases in men.

The most effective way to prevent HPV is vaccination. Currently there are three vaccines available:

-Cervarix: Protection against types 16 and 18
-Gardasil 9: Protection against types 6, 11, 16, 18, 31, 33, 45, 52 and 58
-Gardasil: Protection against types 6, 11, 16 and 18

Captura.PNG

Vaccination is recommended under 11-12 years in order to get protection before starting sexual relations and also because at that age the inmune system is more capable of creating new antibodies. Vaccinations initially started only for girls because the first symptom of HPV detected was neck uterus cancer, but in case vaccination in boys is not improved, starting by 2020 more men will get cancer caused by HPV than women. Vaccines does not contain the complete virus, only some proteins, so it does not have infection capability.

Inmunity last 8 years at least for Gardasil and 9 years at least for Cervarix, however inmunity probably will last longer. Studies about long term inmunity are being made and conclusions are not available yet.

It has been proved that HPV vaccines are also effective for adults, but only for those types that have not been infected yet. However, most of countries only provide free vaccines for the recommended age of vaccination.

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SOURCES

https://www.cdc.gov/std/spanish/vph/stdfact-hpv-vaccine-young-women-s.htm
https://medlineplus.gov/spanish/hpv.html
https://www.cancer.gov/espanol/cancer/causas-prevencion/riesgo/germenes-infecciosos/hoja-informativa-vacuna-vph#q2
https://medlineplus.gov/spanish/news/fullstory_164534.html
https://www.cdc.gov/std/spanish/vph/stdfact-hpv-vaccine-young-women-s.htm
https://www.cdc.gov/spanish/especialesCDC/VacunaVPHvarones/
https://medlineplus.gov/spanish/ency/article/007436.htm
https://www.cdc.gov/spanish/cancer/hpv/statistics/
https://www.cdc.gov/std/spanish/vph/stdfact-hpv-and-men-s.htm
http://www.phac-aspc.gc.ca/std-mts/hpv-vph/hpv-vph-man-eng.php
http://onlinelibrary.wiley.com/doi/10.1002/cncr.29111/full
https://www.aemps.gob.es/cima/especialidad.do?metodo=verPresentaciones&codigo=1151007002

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The most effective way of preventing HPV is abstaining from sex.

The Gardisal vaccination has had devastating effects on many, many young people around the world.

HPV can also be transmited through skin-skin contact, not only by sex. And sex has several health benefits, physiological and psychological.

Vaccines has a very low risk of side effects, especially those that does not contain the full virus like HPV vaccines.

Did you know that 90% of HPV infections correct themselves, without treatment, with in a 2 year period?
Did you know that Gardisal has only been proven to be effective for 5 years? (Yet, they're giving it to kids as young as 11)
Did you know that the Gardisal vaccination includes both aluminum and polysorbate 80?
Did you know that the American College of Paediatritians put out a paper regarding thier concerns for the HPV vaccine and it causing ovarian disfunction in young girls?
Did you know that the doctor who helped design and carry out phase II and III safety and effectiveness studies to get Gardisal aproved, has now spoken out agaisnt its safety?
Did you know that Gardisal has been associated with as many serious adverse reactions as there are deaths from cervical cancer developing each year?
Did you know that Gardisal only prevents cervical cancer caused by 2 types of HPV? (Type 16 and 18)
It does not protect against uterus cancer.
Did you know there where 40 deaths from Gardisal just from the trail studies alone?
As well as another 258 serious adverse reactions? (Study total of just over 29,000 people)
And all of this is just the tip of the iceberg for this vaccine!
Are you reallu that convinced that it has "very low risk of side effects"?

Yes, I know that most of the HPV infections does not cause any symptom. But a minor risk of cancer should be avoided too if possible.

There are not enough long-term studies available to find the time limit of the immunity. According to CDC, immunity last for at least 8 or 9 years. According to theoric models, immunity will last 12 years and 32 years for 50% of vaccinees.
http://www.sciencedirect.com/science/article/pii/S0264410X07002320

Polysorbate 80 is commonly used in foods (for example ice creams) No adverse effects of consuming this substance, except for extremely high doses, has been found. A 2008 study in pregnant rats, with a dose equivalent to 1300g/day for a human of 70kg, only found a significant but no dangerous decrease in weight in the mother.
http://www.sciencedirect.com/science/article/pii/S0890623807002432

Aluminum is proved to increase the immunity response to most virus, so it helps at making the vaccines more effective. It has been used in vaccines for more than 60 years, and the dose received is much lower than received from the diet.
http://www.sciencedirect.com/science/article/pii/S0264410X02001664

I do not care about what any scientist or group of scientist says. Show me the studies about that concerns and then I will be able to give my opinion about that.

Yes, I know that Gardasil only protects against two types of HPV, those that are the main cause of cancer. However there are other vaccines available with protects against more types of HPV. I have told that in my article, seems like you already had an opinion and do not care about my arguments.

So in conclusion yes, I am convinced that it has very low risk of side effects. Show the studies you mention to me and after reading them my opinion may change.

I wrote a blog and tagged you in it which had both source links. Go and have a read.
You said yourself, there is a MINOR risk of cancer, so why the need for a vaccination?
Polysorbate 80 may be commonly used, that doesnt mean it is at all good for you. And there is a very large difference in ingesting something to injecting something. We have a whole digestive system dedicated to breaking down, filtering, and excreting toxins from all sorts of things...we cant do this when it is injected intramuscularly and carried straight into the blood stream.
Polysorbate 80 also opens the blood brain barrier to allow all the other toxins ei. Aluminium, to enter the brain.
Do you know the effects that aluminium has on the brain? The same argument goes for the aluminum, ingested vs injected. As for the dose per vaccination... Did you know that when they say 'trace amounts' that means per single dose. There is 4 doses of a vaccination in one MMRV shot, 4 x a 'trace amount' = a 'not so trace amount'.

I do have my mind made up on this vaccination. I've read a lot of studies, for and aginst, and lot of stories from those injured. Aside from my opinion, one must ask why Japan withdrew its recommendation for the gardisal vaccine in 2013? Or why its been banned completely in Denmark. Other countries to ban it and/or have criminal lawsuits filed include India, France and Spain.

As a suggestion, maybe you could open your mind to the possibility that vaccinations can be very dangerous, and for a lot more people than we have been lead to believe.

The need of vaccination is a subjective consideration. I think current rates of cancer caused by HPV is enough to consider a good idea to get vaccinated. Furthermore, epidemiologic studies are predicting this type infections would increase unless a high amount of population is vaccinated.
http://www.sciencedirect.com/science/article/pii/S0002934397001770

About polysorbate 80 and aluminum seems reasonable that injection may be more harmful than ingestion, but you have not shown any evidence about it.

Japan withdraw recommendation of Gardasil vaccine was a populist decision made without any study or scientific consesus. The Japan Society of Obstetrics and Gynecology demands the resumption of recommendations.
http://www.jsog.or.jp/english/declaration_20150829.html

Danish health authority recommends HPV vaccination: https://www.sst.dk/en/news/2015/the-danish-health-authority-recommends-hpv-vaccination-for-12-year-old-girls

Criminal lawsuits only shows that there is not conspiracy for banning research in side effects of vaccines. Only a sentence may confirm or discredit the effects of vaccines.

In the trail there was 40 deaths, 21 between vaccinated (0,1337%) and 19 between placebo-injected (0,1395%) There was 258 adverse reactions, 128 between vaccinated (0,8150%) and 130 between placebo-injected (0,9547%)

The American College of Paediatritians conclusion was "While there is no strong evidence of a causal relationship between HPV4 and ovarian dysfunction, this information should be public knowledge for physicians and patients considering these vaccines" I agree about more studies should be done with saline placebo, but there is not enough evidence with current studies about those vaccines causing ovarian disfunction.

To be honest, I don't have all the links and sources off hand. As I said, I have read many papers on vaccines.
My mind is made up about this HPV vaccination, but I am not an anti-vaxxer. I think there needs to be a lot more studies on safety and I think that every person should ALWAYS have the right to choose. (with out losing benefits, or rights, etc like we have here in Australia)
I think it is obsurd that all vaccine manufacturers are exempt from responsibility for any damage their products cause.
I do not believe in herd immunity, especially given that we really have no idea how much of the adult population is up to date with their own vaccinations. Here in Australia, our records began in 1996, when I was 10. I know for a fact that I have had at LEAST 8 vaccinations since then, but my record is empty. My husband is the same.
I think there are some serious issues with the current schedule. In particular, the way the doses are combined, with single doses being made unavailable, and the fact that a baby, even premature and small for gestational age babies, are receiving the same size dose as an adult. From 2kg to 200kg, one size fits all! Correct me if I'm wrong, but I don't think there is a single pharmaceutical that is 'one size fits all', why are vaccines different?

We can continue flashing studies around until the cows come home, but while vaccination exists the argument will always remain. I just wish that no more children have to suffer before the extent of the damage is realised.

Thank you for being respectful during our debate.

"I just wish that no more children have to suffer before the extent of the damage is realised"

I wish the same. The difference is that I think that the best way to reduce the suffer of the children is to improve vaccination. More studies on safety are always good, but how much studies are enough? The more we wait until we consider a vaccine is safe, the more people dies for the virus until the studies are completed. A 30 year study should have made before starting massive vaccination of smallpox? How much people would have died in that period of time?

I agree about every person should always have right to choose, and that right includes the right to be properly informed about that. I try to inform the people the best I can. Most anti-vaccine arguments are false or can be misunderstood, and this I was tried to show in that conversation. I am not telling that all the arguments are wrong, of course.

As far as I know there is no different sizes of vaccines according to age, but the limits in some ingredients like aluminum and mercury are more strict for children and babies.

Good topic, but I've found I get more votes if I write in the style of a research paper in the science and SteemSTEM tags.

Thanks, I thought informative articles would have a better reception.

May you show me an example of the paper style you mention, please?

If you're posting in science and/or tech or education try using the tag "steemstem."
In my case, some of my posts are actually research papers about original research in my own lab. Some projects were already written up but never published before my retirement. So, they were already in a typical layout for a scientific paper. Also, I've been able to reconstruct lost data and share it with my former colleagues. Here is the post of mine that got a steemstem and a curie upvote, and one was in the weekly Steemstem distilled:
https://steemit.com/steemstem/@steemstem/steemstem-distilled-44#@davidrhodes124/re-steemstem-steemstem-distilled-44-20180430t224848069z
https://steemit.com/science/@qiyi/quantitative-real-time-pcr-assays-of-bacterial-dna-in-biomarkers-for-nitrospira-sediments-of-the-flint-mammoth-cave-system
https://steemit.com/science/@qiyi/quantification-and-characterization-of-a-bacterial-community-in-sediments-from-mammoth-cave
https://steemit.com/steemstem/@qiyi/artificial-substrates-for-analysis-of-bacterial-biofilms-in-aquifers-of-mammoth-cave
https://steemit.com/science/@qiyi/quantitative-pcr-a-brief-introduction

Thanks a lot!

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