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RE: Nrf2: The cellular guardian against oxidative stress.
And since they are mainly formed during metabolism, which takes place in the mitochondria and thus in the cells
I thought that their main source is inflammation.
It is already known that inflammation accelerates aging and also known that ROS are used to fight infections, either as external disinfectants (such as H2O2 solutions) or internally, by the immune system.
Another question is does stress directly increase formation of ROS, or not?
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inflammation does cause oxidative stress too (as a mode of combating infections, as you correctly state), but they are not the prime source of ROS. ROS are constantly produced by metabolic reactions.
It's the other way round. An increased formation of ROS causes stress.
Ty for commenting, btw.
Were the respective amounts measured?
In the sense of increased cortisol production?
Ty for replying.
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