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RE: Mitochondrial medicine: Fact or fiction? Part II – Mitochondria and the cellular crosstalk.
I really enjoy reading those posts… and actually what I enjoyed the most are the home-made pictures (especially the pacman ones). :)
I have a small question this time:
Current estimations come to the conclusion that one in 2000 persons suffer from a mitochondrial dysfunction [1].
This corresponds to a huge fraction of the population, doesn’t it? But I guess those numbers account both from the positive mutations and negative ones all together (cf. your point 1).
Hey @lemouth,
it's fine that you are enjoying my pix.
Concerning your question:
No, the number corresponds primarily to category 2. & 4.
Everyone belongs to category 1., that's your heritage and in general, you don't suffer from them.
Nevertheless, it is a variation in function and could, therefore, be a potential problem.
But you are right 1 in 2000 are a lot and there are much more people affected because this is a number belongs to clear characterized mutations. Other problems are not taken into account thus far!
Regards,
Chapper
Ok sorry, I got it wrong. But do we agree that this 1/2000 always refers to dysfunctions. As a mutation does not necessarily imply a dysfunction, doesn't it?
You got it!