With people is the better one.

With or without people generally, it depends on the subject. Sometimes I wait for people to leave, sometimes I wait for people to arrive. It all depends. And when people see that I'm taking a photograph, some do the weirdest thing. They want to walk, but they can't and they stop to wait or they (almost) duck walk (which looks funny), because they think that I cannot take the photo any time I want to. They can't act normally and walk by if they see me. :D