New variants of SARS-CoV-2

in Project HOPE4 years ago

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Since human beings began to be infected by viruses, we also began to look for ways to counteract the undesirable effects of these infections.
As a consequence of these protection mechanisms, the molecular structures of viruses began to mutate, developing new mechanisms to gain entry into our cells. This phenomenon is called "mutation."

When a virus enters our cells, it begins to replicate and frequent changes occur in some of the amino acids that make up the virus proteins. As a consequence, the molecular structure is altered, and with it the properties of the virus.


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New variants of SARS-CoV-2

Currently, new versions of the virus are appearing. This is because at the beginning there were no methods to combat it, we were more susceptible, therefore, the transmission occurred in its native form.

Today, many people have already passed the infection and have antibodies against the virus. The use of allows to avoid contagions with good ventilation, and a global vaccination process has also begun.

These protection measures have caused changes (mutations) in the molecular structure of the virus, one of which is the increase in its ability to interact with the cell receptor.

The variants of SARS-CoV-2 that are worrying scientists, due to their speed of transmission, are the Brazilian, the South African and the British.

One of these mutations consists of a change in the structure that allows binding to the cell receptor, therefore contagion is faster and the spread can be greater, in addition to favoring binding to the receptor, it could make the virus more resistant to antibodies, thus increasing reinfections or decreasing the effectiveness of vaccines.

These variants can favor the spread in non-human species, which would allow the appearance of new strains that are more dangerous for people.


Conclusion

As new variants of the virus continue to emerge, there will be a greater number of infections and consequently, a greater number of victims.

Elderly people would be the most vulnerable because their bodies have less production of antibodies that are our natural protection, although all, in general, are susceptible to contagion and it is increasingly difficult to treat the sick.

The circulation of these variants will also affect the efficacy of vaccines and the frequency of reinfections,

Most of the studies have been carried out in in-vitro tests, which do not take into account the complex immune response that is generated in an organism. By confirming the lower effectiveness of the vaccines on these variants, it would imply that the vaccines would have to be updated based on the appearance of new strains, which would slow down the immunization process at a global level.

For all the above, we can assume that we still have a long way to go in this process of fighting the virus and humanity will have to continue modifying their daily routines of life in order to achieve survival.


@juanmolina


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Every medal has two sides. We got used to treat OCVID as invisible predator that wants to kill you. The truth is that virus doesn't want to kill you. It wants to replicate and for this host needs to be alive. It surely mutates to spread faster, it will also mutate to be less deadly.

 4 years ago 

...it will also mutate to be less deadly.

Interesting speech.
I hope it happens this way.

Thanks for stopping by and commenting.

Hello @juanmolina

As new variants of the virus continue to emerge, there will be a greater number of infections and consequently, a greater number of victims.

Correct, and precisely this alarming situation has been triggered by ourselves, and I say we, to refer to the world society, since the greater the number of infections the strains tend to present a higher degree of pathogenicity, and therefore can reach greater virulence. The opposite would have happened if the isolation and quarantine methods had been respected, since in cases where there is no host the virus weakens or in other words becomes less aggressive. Unfortunately, the situation may worsen in the following months. Best regards, be well.

 4 years ago 

In my opinion, the virus will be overcome once our organisms manage to generate antibodies naturally. Unfortunately for this to happen we must be infected and not all of us have the necessary resistance. Therefore there will be more deaths. It is a very worrying dilemma.

Hello friend, the truth is that this virus has taken us all by surprise and today there is talk about its mutations, it is a difficult situation because as you say it worsens the whole picture and the vaccine that is already established would be useless. I think it is a very difficult situation for the health profession and also people do not do their part, they do not take care of themselves or others, so it is much more difficult to fight any disease. Greetings!

 4 years ago 

I am very concerned that the development of the vaccine is taken as something commercial.

Many will benefit financially from these vaccines, which will never be fully effective, especially with the new mutations that are occurring in the original strain.

Hello my friend @juanmolina,
Very explicit information that we comportes, it is certainly alarming the situation that is occurring as a result of the convid-19, but more alarming is the future that is looming because of the mutations that is presenting at the structural level this virus. The sad thing of all is that young people do not seem to care about what is happening and the countless victims who have lost the battle, and isolation and social distancing are not enough. Thank you for your contribution

 4 years ago 

All the viruses that humanity faces behave in a similar way. For example, the common flu virus is always present, so we eventually catch a cold.
The concern about Covid corresponds to the high levels of lethality.
We must continue to take care of ourselves and wear masks.

Stay safe dear friend.

Hi @juanmolina
I'm afraid this pandemic situation could even continue for this year. Because of what you mention. And also I think that those vaccines that are being applied, although they are effective against the original strain of the virus, may not be the same in those that are already and much less in those that are going to emerge. So all this leaves us with a rather complex panorama.
We still have to be careful, keep inventing things to produce in case all this goes on for much longer.
Which is most likely.

 4 years ago 

That's right, my friend, even scientists have a lot to experiment, a lot to discover, to achieve an optimal level of immunization.
In the meantime, it is up to us as a population to adopt the preventive measures.

incredible the mutuality of this malignant virus, your information is important and you will see thanks friend

 4 years ago 

My pleasure, thank you.

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