I became interested in the liposomal vit C after watching a Youtube titled "liposomal vitamin c 60 minutes". Taking regular vit C isn't absorbed as well in high doses. Some doctors use IV vit C therapy -- but the liposomal form is absorbed well enough. As far as studies go, high dose vit C for therapeutic purposes is usually considered "alternative". Websites that deal with natural remedies contain a lot of articles about it -- and greenmedinfo.com has a lot of info on therapeutic vit C: http://www.greenmedinfo.com/blog/clinical-impact-vitamin-c-my-personal-experiences-physician