Hey @jeff-kubitz... I agree there are some supplements out there that do as they claim.., but very few... The two places I mentioned above "Dragon Herbs" and "Longevity Warehouse" have some amazing supplements but are not the "run of the mill" vitamin or supplement you find at the local drug store. As for your colon -- just get a colonic if you need to clean yourself out -- they're great. Cheers Buddy and thanks for such a concise comment!