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The FDA Just Approved PayPal Founder’s Project to Use Magic Mushrooms to Treat Depression

in health •  29 days ago

 

This week, it was announced that a startup called Compass Pathways  has received approval from The Food and Drug Administration to develop  treatments for depression, and possibly even pharmaceuticals, with psilocybin, the active ingredient in psychedelic “magic mushrooms.” Compass Pathways launched in the UK in 2016, thanks to funding from  Peter Thiel. 

While the company is just now receiving approval to run  trials in the US, they were already approved in Canada, the Netherlands  and their base of operations in the UK. 

According to the company’s website,  the trials will take place across 15 different sites throughout Europe  and North America, and will involve 216 participants. The tests are  expected to begin in the UK by the end of August. 

“This summer we are beginning a randomised controlled trial of  psilocybin therapy for treatment-resistant depression. This will be the  largest clinical study of its kind and will take place in a number of  clinical trial sites across Europe. The trial is a phase IIb  dose-ranging study with 216 patients. If successful, it will be followed  by phase III studies in which we will look at comparing the optimal  dose, mostly likely to placebo or standard of care,” a statement from the company said. George Goldsmith, chairman, and co-founder of Compass Pathways told FoxBusiness that these trials will help his team learn exactly how they can use psilocybin to treat depression. 

“Depression is the leading cause of ill-health and disability  worldwide, and treatment-resistant depression affects more than 100  million people. It is a huge unmet need and the trial will teach us more  about how this new approach might address it,” Goldsmith said. 

These trials will undoubtedly add to the wave of psychedelic studies  that are being carried about by a growing number of brave researchers. 

A report in The Journal of Psychopharmacology suggested  that psilocybin mushrooms could help long-time smokers kick their  habit. The report sourced a recent John Hopkins study, authored by  Matthew W. Johnson, an associate professor of psychiatry and behavioral  sciences at the Johns Hopkins University School of Medicine. The study  featured a small test sample but is one of a series of studies that are  showing the healing powers of psychedelic compounds. In 2012, John Hopkins made news in psychedelic research with a study showing that the psychedelic experience can help terminally ill patients come to terms with their own mortality. According to a new study from the Psychedelic Research Group at Imperial College London, published in the journal Psychopharmacology,  psychedelic mushrooms tend to make people more resistant to authority.  They also found the psychedelic experience induced by these mushrooms  also cause people to be more connected with nature. 

In another recent study,  researchers at the University of Zurich dosed 24 people with 100  micrograms of LSD and essentially found that these test subjects  experienced a diminishing of their ego and reported that they felt more  connected to the people around them. Prior research has also indicated that Theil’s bet on psychedelic therapy for depression could pay off big. 

These possibilities have also been explored by a team of researchers  from The University of North Carolina, Stanford University and the  University of California, who determined that LSD could, in fact, be  used to treat schizophrenia and depression. 

The researchers used a process known as crystallography, in which  atomic and molecular structure of certain interactions are studied. Specifically, the researchers were able to discover how LSD molecules  interact with the serotonin receptors in our brain. Researchers plan on  using this knowledge to develop an LSD based treatment for people with  schizophrenia.

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I am always suspicious when the "FDA approves...something" - it usually means that Big Pharma is about to take over and make something that we have been using for centuries into a patented "medicine" that only certain people have access to. Revenue - it's aaaalll about the $$

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who pays for drugs themselves out of pocket?

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I do not. but I don't use "drugs" at all so I don't know.

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prescription drugs are so expensive because most of the people who use them don't even know what they cost and government subsidies create price floors.

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you are right @funhobby51 - I remember one time I had an absessed tooth and my dentist gave me a perscription for an antibiotic. I went to walgreens to fill the perscription and tried to use my homedepot employee perscription discount card and they said it would be $400 - I called my dentist who sent me to walmart (I never go there) and I went without the discount card and it was $4 - WTF??? all I could guess was that it was the highway robbery of the ins co's that made that happen that way - and people's inattentiveness to the process has made this the fact today.

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same with MRIs and all other medical care, I got an MRI not too long ago and they had sent me to the hospital to have it done but then my wife found out and I went to the MRI place a quarter mile from the hospital, the same MRI company and it was like $600 less. And they were all confused why I was even asking.

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what the fuck - that is insane!!! gone are the days when we were fully self-supporting - and using ins co's has driven prices up to the point where ins co's have built a nest on the ground, i guess... wow.

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that and a lot of people are on government insurance and they really don't give a shit what things cost. no provider would ever provide any service for less than whatever the government is willing to pay, it makes a price floor and kills competition even more.

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I was thinking the same thing. When has the FDA ever approved something that can be grown by anyone?

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weed - hemp - but only so they can take it over.

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I'm as on edge as you are about this. God and Goddess gave us these things to be used in a certain manner ... that is, naturally. I would understand science getting involved if there was a toxin or something in it that made it dangerous for humans to consume naturally, (for there are tons of substances like that; take the Daturas, for instance, I wouldn't touch them with a 1-foot pole, keeping my respectful distance from them grown in gardens), but other than that, what we put in our bodies and reasons for it are our decisions to make, not the government's. I have never encountered the mushroom experience, though I would much rather try mushrooms over LSD ... for the same reason. Mushrooms come from nature, whereas LSD is synthetic, hence can't teach us anything. If I try, I want to try in the way the higher powers intended for us to try, not based on some bullshit pharmaseudical.

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I have taken shrooms - but I don't take any pharmaceuticals at all. Now, I just go for direct contact with the Spiritual realm without the use of anything.

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Same here. I have no problem with that at all, after all, I think I was actually born for it. I'll be sharing some stories later on and some more posts, so follow me if you're interested. Of Adventures in my life on that side of things, it's been both fun and scary at the same time.

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mushrooms are great but they are not going to cure depression, tolerance develops very quickly, they would need to double to dose daily to get the same effect. They have already developed a non psychedelic version of LSD that works very well for otherwise untreatable and debilitating cluster headaches.

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