The Prion Protein & Prion Diseases

The Prion Protein, PrP

Protein only related diseases

Today i would like to introduce you to a fascinating yet lethal protein, the Prion Protein, or PrP for short. This post will be much shorter than usual and focus on the dangers with animal proteins and thereby meat.

This is arguably the most well studied protein in history of biochemistry, yet still, its mechanisms of infection has been elusive to find, saying the very least.
Today we know that one infectious Prion protein originates from bovine cells and infects humans via eating the cow meat. I would never eat meat again after educating myself in biochemistry for 5 years, trust me it is dangerous in many ways.

The studies of PrP has resulted in two nobel prizes, first in 1976 when the first prion disease where found and later in 1997 for the protein only hypothesis!

The prion protein is a small protein, consisting only of 253 amino acids and folds into 3 alpha-helical regions. In this confirmation the protein is safe and not infectious, but with 1 single region changed into a beta-sheet, the protein becomes infectious by helping more Prion protein change confirmation and do the same.

"One Alpha helics is altered into a beeta sheet, turning PrP infectious to other PrPs".


This generates a cascade effect, or chain effect rather of Prion proteins being altered.
In the human body, PrP folds into PrPc, the noninfectious strain under physiological conditions, meaning 37 degrees and pH 7. Acidic conditions,meaning lower pH, has been proved to promote Beta sheet formation.

The alteration makes PrP resistant to protease binding and thereby resistant to being broken down and instead the proteins clump together and form prion plaques or prion rods. The most commonly affected areas is the cerebellum and the frontal cortex in the brain.

The most common disease affecting humans is Classic CJD, or Creutzfeldt Jakob´s disease.
The symptoms will include personality changes and movement problems as the disease progresses since it primary hits the brain.
CJD originates from cow meat or products containing cow intestines but the diagnosis is still rare. The cows suffer a terrible disease called Mad Cow disease which can spread to humans and result in CJD.
The progression is very slow, it might take over 10 years for a human infected by CJD to manifest any symptoms so the disease might be spreading under the radar. This disease is primarily seen is the USA and Europe just as Alzheimer´s disease making me very suspicious to consuming meat. Personally i am a vegetarian trying to stay 100% vegan and without needing moral or spiritual reasons, which i also have, i would never consume meat under any circumstances!

Sheep are also affected by prion a disease called Sheep scrapie causing neurodegenerative symptoms just like CJD.

Figure
Another prion disease, even more rare which affects humans is Kuru.
Kuru was found at Papua New Guinea under the 1950´s and has it´s roots in cannibalism, yes, you heard me, cannibalism!

Humans that are eating humans suffer a horrific disease, breakdown of the brain, aggression and madness, just as some of the bovine meat eaters do.

This is only the second post on Amyloid proteins that are killing us, and much more to is to come. All of them have proteins in common, miss folded or infectious proteins either as a result of genetics or environmental. I would guess that the environmental aspects is the biggest drive behind Alzheimer´s disease and prion diseases since most of the patients reside in the USA.
We eat meat as a source of protein, but eating animal cells apparently come with many dangers and i would advice you to search for healthier protein sources as well as never exceed 10% of your food weight in protein.

Many humans in todays society think that we need 20% protein to workout, this is madness and deception!

• An elephant growing TONS of muscle and need merely grass and some fruit!
• The blue whale calves grow 90 KG A DAY, muscle beasts, while drinking milk and never exceeding 6% of protein.
• Human babies grow much much more muscle seen as % of the weight, then we do in any other age and they never exceed 6% protein either, this is merely dangerous!

I think that numerous death´s from Alzheimer´s disease which affects 5 million US citizens, is miss diagnosed prion diseases, wake up!

Meat kills you in many other ways, check my post on glyphosate if you want more reasons to go vegan and avoid pesticides. Animal eat glyphosate sprayed crops as well as we do, and they are having a bad time.
While being slaughters the intestines of many pigs fall apart and smell terribly bad showing how glyphosate affects the gut. Leaky gut has become a big problem and linked autoimmune diseases like MS.
Do not eat glyphosate!

--> Glyphosate Article here <--

Help yourself and help the suffering animals, do NOT eat, buy, or in anyway support the meat industry it is insanity.

Figure


Thanks for checking the post out, raise awareness, Upvote & Resteem!