Definitely Dead Space 2.
It was like 4 am in the morning and I was playing this game..I was making sure not to get scared by turning the light on, then mute the game and turn loud the music..nothing wrong but the thing was that because of the bass of the music (I was having the audio system on a shelf above me) exactly when I was fighting a boss, my collection of cans started falling right in my head and desk creating a huge sound followed by my screams, lol
It was a crazy night filled with no sleep, doors closed and uninstalling that game, haha