Original text:
He had to ignore his senses, his instincts as here neither couldn't be trusted.

The double negative in this sentence got me confused, then I saw that it made no sense. There are several ways to fix this.

1. He had to ignore his senses, his instincts, as here neither could be trusted.
2. He had to ignore his senses and his instincts, as here neither could be trusted.
3. He had to ignore his senses and instincts, as here neither could be trusted.
4. He had to ignore his senses and instincts, as they couldn't be trusted here.
5. He had to ignore his senses and his instincts, as they couldn't be trusted here.