A nexus will appear to force thy path, beware all is lost if your path is not true.

I wonder if it alludes to the "Dead Space", In a previous segment there was a dead space graveyard, ships lost in time. I guess it could also be that Alienbutt is like really upset when he gets back, or a warning of Mr Fluffy, it seems the Ick don't really know of him yet, at least Nifty can fill them in when she gets there.