I use copic multiliners. That come in many colors. They are great for drawing manga like characters, where you use a dark peach for the edges of skin, instead of a heavy black line.

I have mixed feelings about what I would do with this piece.

A. shade it in with india ink
B. shade it in with colored ink.

There was a blue ink that I had that, with various dilutions, could make this very close to water crystal colors.

But I do not think black and white will work for this. Its not the right amount of busy. But, but, I have seen you pull off other things with just a pen, so...