have you had a chance to watch the show on Syfy "The Expanse" ... its basically this, colonize Mars, some space stations around, colonize our moon and other planet moons ... and then a bunch of stations built into larger asteroids that are caught in the battle between the sun and Saturn's gravity :)

I think thou, if disaster is to strike, its because we created it, and chances are all humans in the system will get sucked into the disaster and or its aftermath ...