Ulog day #05 | Spironolactone and furosemide reactions

Both spironolactone and furosemide are both drugs of a diuretic class that can reduce the burden of the heart. Both can reduce swelling due to fluid, including swelling in the lung (pulmonary edema) and also swelling in the limb due to heart failure.



Spironolactone can withstand potassium while furosemide is the opposite. Consumption of furosemide may increase urinary potassium expenditure so that patients taking furosemide are often given potassium supplements to compensate. Low or excessive potassium in the blood can disrupt the heart.


Spironolactone preparations are 25 mg, 50 mg, and 100 mg while furosemide 20 mg and 40 mg. In heart failure, the dose given is usually low dose. Spironolactone and furosemide may be administered simultaneously, but usually at low doses and of course with consideration of treating physicians (judgment based on clinical conditions: swelling, spasms, blood potassium levels, etc.).

In addition to the clinical state of the patient when examined, drug administration by the physician is also influenced by the clinical experience of each physician.

May be useful,