Anti-HIV Super Supplement Stack: Potential prevention, treatment, cure for the HIV virus?
"Currently, the most effective treatment for HIV was HAART, which stands for "highly active anti-retroviral therapy." HAART suppresses HIV through its combination of medications and has greatly improved patient outcome. However, it does not cure the infection. Instead, HAART leaves reservoirs of the latent HIV in memory CD4+ T cells, a type of cell involved in the body's immune system."
"In order for the latent cells to be eliminated, they must first be activated so the virus can be detected by the body's immune system. But there are complications that can arise when activating the HIV."
https://www.jhunewsletter.com/article/2009/10/compound-from-black-walnut-tree-fights-hiv-45782/
"Stacking supplements has many benefits. For one, there are many ways to gain muscle or lose fat, so by combining supplements that help you do either one through different pathways is very important."
https://www.bodybuilding.com/content/what-are-the-best-supplement-stacks.html
"The half-life of the drug is useful in determining the dosing frequency"
https://www.medicinenet.com/what_does_half_life_mean_in_drugs/article.htm
"Creatine is a generally well tolerated, low-cost, over-the-counter nutritional supplement that shows potential in improving lean body mass and functionality in patients with wasting diseases. However, placebo-controlled studies have shown variable effects, with improvements in some and not in others."
https://pubmed.ncbi.nlm.nih.gov/19741514/
"There is compelling evidence that micronutrient deficiencies can profoundly affect immunity; micronutrient deficiencies are widely seen in HIV, even in asymptomatic patients. Direct relationships have been found between deficiencies of specific nutrients, such as vitamins A and B12, and a decline in CD4 counts."
https://pubmed.ncbi.nlm.nih.gov/10696118/
"An extract from a plant used in traditional Chinese medicine may help protect the genes of immune system cells and, as a result, enhance their ability to fight HIV, according to a new study announced by the University of California Los Angeles (UCLA) and published in The Journal of Immunology."
https://www.poz.com/article/hiv-astragalus-telomere-15595-6219
"Ayurvedic practitioners prescribe ashwagandha to rejuvenate the immune system of HIV-positive people. Animal studies have shown that the herb improves the immune responses of mice that are given immunosuppressive drugs and helps mice resist tumours and other cancers. There are, however, no studies specific to HIV. Ashwagandha may also help treat muscle wasting, which is associated with HIV."
https://www.thebody.com/article/herbal-therapies-used-people-living-hiv-ashwagandha
"To treat HIV and AIDS
Lab studies suggest cat’s claw can stimulate specific immune cells, but human studies are needed."
https://www.mskcc.org/cancer-care/integrative-medicine/herbs/cat-claw
"Researchers are focusing on an extract of garlic called ajoene which also appears to protect CD+ cells from attack by HIV early in the viral life cycle. At low concentrations, the drug appears to have little toxicity, and its anti-HIV activity is 45 times more powerful than the drug dextran sulfate. Ajoene is found only in fresh garlic and is not readily available."
https://pubmed.ncbi.nlm.nih.gov/11365438/
"Natural products from herbs with the abilities to inhibit HIV-1 life cycle at different stages, have served as excellent sources of new anti-HIV-1 drugs."
"The dandelion extract showed strong activity against HIV-1 RT and inhibited both the HIV-1 vector and the hybrid-MoMuLV/MoMuSV retrovirus replication."
https://pubmed.ncbi.nlm.nih.gov/22078030/
"bromelain can tear apart the outer protective envelope of certain viruses like HIV, HPV and Hepatitis C."
https://losethebackpain.com/health-benefits-bromelain/
"Antiviral fatty acids were found to affect the viral envelope, causing leakage and at higher concentrations, a complete disintegration of the envelope and the viral particles."
https://pubmed.ncbi.nlm.nih.gov/3032090/
"Due to its antiviral effects and its importance for all immunological functions, the administration of selenium is suggested as a supportive measure in early as well as in advanced stages of HIV-induced disease. Initial observations on the effects of selenium supplementation in HIV-infected patients indicate that selenium causes symptomatic improvements and possibly slows the course of the disease. As selenium inhibits reverse transcriptase activity in RNA-virus-infected animals, supplemental selenium could also prevent the replication of HIV and retard the development of AIDS in newly HIV-infected subjects."
https://pubmed.ncbi.nlm.nih.gov/7514960/
"Patients with low vitamin B-12 levels showed lower hemoglobin, leukocytes, lymphocytes, CD4 lymphocytes and CD4/CD8 lymphocyte ratio than HIV patients with physiological serum vitamin B-12 levels."
https://pubmed.ncbi.nlm.nih.gov/1868915/
"A growing amount of data over the last years have shown vitamin D deficiency to be high prevalent among HIV-positive subjects."
https://pubmed.ncbi.nlm.nih.gov/23690192/
"HIV/AIDS patients are probably more predisposed to vitamin E deficiency, considering that they are more exposed to oxidative stress. Additionally, there are an extensive number of drugs in the highly active antiretroviral therapy (HAART) regimens that may interfere with vitamin E concentrations."
https://pubmed.ncbi.nlm.nih.gov/25225815/
"Individuals with HIV are at increased risk for osteoporosis. A healthy diet with adequate Ca is recommended to promote bone health."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600937/
"There is a quadratic relation between the serum magnesium level and the number of CD4 lymphocytes in HIV-AIDS patients studied. A larger number of cases would allow us to conclude whether hypomagnesemia is a factor belonging to the disease, as well showing the possible differences in the magnesium state between the three diagnostic groups studied. Future studies will be necessary to clarify the role of magnesium in the clinical progression of patients infected by HIV."
https://pubmed.ncbi.nlm.nih.gov/9477656/
"increasing manganese in cells can halt HIV's unusual ability to process its genetic information backwards, providing a new way to target the process's key driver, an enzyme called reverse transcriptase"
https://www.sciencedaily.com/releases/2002/04/020429072353.htm
"The use of nanoparticles (NPs) for the treatment and prevention of HIV/AIDS is an emerging technology of the 21st century. NPs are solid and colloid particles with 10 nm to <1000 nm size range; although, less than 200 nm is the recommended size for nanomedical usage. There are NPs with therapeutic capabilities such as liposomes, micelles, dendrimers and nanocapsules. The particle enters the body mainly via oral intake, direct injection and inhalation. It has been proven to have potentials of advancing the prevention and treatment of the viral agent. Certain NPs have been shown to have selftherapeutic activity for the virus in vitro."
https://pubmed.ncbi.nlm.nih.gov/31250759/
"zinc can inhibit reverse transcriptase in HIV."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349606/
"silver nanoparticles inhibit post-entry stages of the HIV-1 life cycle."
https://pubmed.ncbi.nlm.nih.gov/20145735/
"Heavy metals including gold and silver are antibacterial, but copper’s specific atomic makeup gives it extra killing power, Keevil says. Copper has a free electron in its outer orbital shell of electrons that easily takes part in oxidation-reduction reactions (which also makes the metal a good conductor). As a result, Schmidt says, it becomes a “molecular oxygen grenade.” Silver and gold don’t have the free electron, so they are less reactive."
https://www.smithsonianmag.com/science-nature/copper-virus-kill-180974655/
"The mechanism of gold nanoparticles against HIV-1 is not clear but it inhibits the HIV-1 fusion. In this study, the gold nanoparticles were used to analyze their mode of antiviral activity and the experimental results showed that they inhibit the viral entry by binding with gp120 and prevent CD4 attachment. These properties of gold nanoparticles make them as an effective antiviral inhibitor."
https://pubmed.ncbi.nlm.nih.gov/22954307/
"Numerous in vitro studies have reported that artemisinins have antiviral properties. Artemisinins reduce replication rates of hepatitis B and C viruses 31, 32, a range of human herpes viruses 33, 34, 35, HIV-1 36, influenza virus A 37, 38, and a bovine viral diarrhea virus39, in the low micromolar range."
https://www.biologicalmedicineinstitute.com/post/artemisia-annua-a-potent-antimicrobial
"These results indicate that GL inhibits R5 HIV replication in fresh PBM/MA through the inhibiting CCR5 expression mediated by CCL2 or IL-10."
https://pubmed.ncbi.nlm.nih.gov/15860928/
"Further research is required to determine the potential role of CLA isomers as therapeutic agents in the management of HIV-associated lipodystrophy."
https://pubmed.ncbi.nlm.nih.gov/27924729/
"Alpha-lipoic acid, a naturally occurring disulfide-compound that acts as a cellular coenzyme, inhibits replication of HIV-1 in cultured lymphoid T-cells."
https://pubmed.ncbi.nlm.nih.gov/1724477/
"Epigallocatechin gallate (EGCG), the most abundant catechin in green tea, has been reported to inhibit HIV-1 replication prior to its integration into host DNA via various proposed mechanisms; however, the specific main target(s) of EGCG remain unclear."
https://pubmed.ncbi.nlm.nih.gov/21730371/
"However, we found that p38 MAP kinase and JNK1 and -2 were activated by St. John's wort, but p44/42 MAP kinase was not activated by St. John's wort in HeLa cells. Hypericin an active ingredient in St. John's wort also inhibited the UV activation of HIV gene expression in HeLa cells. These results firmly confirm that St. John's wort is a potent inhibitor of the UV-induced activation of HIV gene expression in HeLa cells."
https://pubmed.ncbi.nlm.nih.gov/12665247/
"We find that OLE inhibits acute infection and cell-to-cell transmission of HIV-1 as assayed by syncytia formation using uninfected MT2 cells co-cultured with HIV-1-infected H9 T lymphocytes. OLE also inhibits HIV-1 replication as assayed by p24 expression in infected H9 cells. These anti-HIV effects of OLE are dose dependent, with EC(50)s of around 0.2 microg/ml. In the effective dose range, no cytotoxicity on uninfected target cells was detected"
https://pubmed.ncbi.nlm.nih.gov/12878215/
"Our results showed that GSE significantly downregulated the expression of the HIV-1 entry co-receptors, CCR2b, CCR3 and CCR5 in normal PBMC in a dose dependent manner."
https://pubmed.ncbi.nlm.nih.gov/12462994/
"The findings reveal the potential of chitosan nanocarriers as vehicles for anti-HIV-1 drugs [61]."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557018/
Oregano Oil and Its Principal Component, Carvacrol, Inhibit HIV-1 Fusion into Target Cells
https://pubmed.ncbi.nlm.nih.gov/32461309/
"Iodine kills bacteria, viruses, fungi, protozoa, and even spores of bacteria and fungi, including anthrax spores. Iodine was used successfully against influenza, herpes, small pox, and chicken pox viruses.
No organism develops resistance to iodine."
https://whyiodine.com/iodine-the-most-effective-agent-for-killing-viruses/
"Cannabinoids have been shown to inhibit productive HIV infection in primary human T cells, and a CB2 antagonist blocked this effect"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340429/
Curcumin inhibits HIV-1 by promoting Tat protein degradation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901322/
**Glutathione inhibits HIV replication by acting at late stages of the virus life cycle **
https://pubmed.ncbi.nlm.nih.gov/8911579/
Quercetin synergistically reactivates human immunodeficiency virus type 1 latency by activating nuclear factor‑κB
https://pubmed.ncbi.nlm.nih.gov/29207194/
Antioxidants inhibit stimulation of HIV transcription
https://pubmed.ncbi.nlm.nih.gov/8512745/
Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry
https://pubmed.ncbi.nlm.nih.gov/11027509/
Inhibitory activity of flavonoids and tannins against HIV-1 protease
https://pubmed.ncbi.nlm.nih.gov/10993207/
L-carnitine reduces lymphocyte apoptosis and oxidant stress in HIV-1-infected subjects treated with zidovudine and didanosine
https://pubmed.ncbi.nlm.nih.gov/12215207/
The supplement Dr. Fauci takes to help keep his immune system healthy
https://www.cnbc.com/2020/09/14/supplements-white-house-advisor-fauci-takes-every-day-to-help-keep-his-immune-system-healthy.html