You are viewing a single comment's thread from:
RE: Understanding Correlation measurements of Protein motions from MD trajectories
Interesting. So where all is correlation mapping used? And are correlation maps result if MD simulations or they are made from wet lab experimental data?
Ok think about a case to see how processes like allostery propagates in a protein or protein protein complex. (Or it can be any bio molecular complex) using correlation maps you can see how the signal propagates. Like we can see how a region interacts with other. Whether it is a repulsive interaction or not. But bare in mind about caveats. It doesn't imply causation.
These maps are usually results of MD simulations. I don't think wet lab experiments can get data with this resolution. And the time scale for averaging to get these maps are of the order of nanoseconds.
Let me know if I answered your questions.