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RE: Obesity and the DNA Repair Protein OGG1
My first time of hearing about DNA repair protein.
The part where mentioned that "Dysfunction of OGG1 has been implicated in cancer" left me wondering.. Does it mean that cancer patients have mutilated OGG1? Now that sounds pretty scary :(
No, not necessarily. A mutation to OGG1 does not seem to actually result in cancer, there are likely other enzymes with overlapping activity which can also deal with 8OxoG, making OGG1 good to have but not essential.