I answered the very same comment a bit further above. Fundamental physics is extremely picky, and probably one of the most picky science. But of course the level of pickiness is relative to the experimental context, how experiments can be built, etc... I can easily imagine that in biology, 0.05 is already not easy to get. FYI, we use 0.05 to exclude hypotheses, but not for discoveries (where we ask for more).