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RE: Obesity and the DNA Repair Protein OGG1
Mitochondria is the powerhouse of a cell. So you're saying that a lack of this OOG1 protein could alter the mitochondria's metabolic activity which be the possible cause of obesity?
Not the cause, but their is already sufficient literature available studying humans which indicate that obesity often coincides with reduced expression of OGG1. This study illustrates that the opposite (increased OGG1) results in resistance to weight gain.
Its clearly safe to say that OGG1 plays a metabolic role and is a contributing factor in why some people becoming obese. Just not necessarily the only factor.
Great question!