RE: Critical Review of a recently published discovery that RNA can induce an epigenetic engram (memory)

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RE: Critical Review of a recently published discovery that RNA can induce an epigenetic engram (memory)

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effofex (62)in #steemstem • 7 years ago

Or the famous "Arsenic-based DNA" that was a complete blunder

That and the planarian experiment @rcebike has already mentioned were my first two thoughts when reading about that. I'm glad others are looking at this with a wary eye and are waiting for independent labs to replicate it.

Why are the controls so much different?

But you see, all we care about are those little ** p-value indicators. :(

7 years ago in #steemstem by effofex (62)

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alexs1320 (71) 7 years ago

There are several indications that the whole idea could easily stay on the "promising results":

if they really have this, why they stopped instead of going on the molecular level so they could publish in the holy trinity (Nature, Science or Cell)
the research group is not really focused on this topic
the measurement of the reflex seems very subjective to me (their video):

Are there any other reasons why the snails would decide to act faster/ slower? Keeping that in mind, I was very surprised that the first control was almost without the error (something like 1, ε0.1 ). But after getting the RNA from the untrained animals, error bar became hudge. And the average as well (it looks like 6, ε=4)

And the last thing. Snails are strange animals. We are not trained to observe their feelings. I know when I looked my Tardigrades that some of them were completely inactive others made some claw movements, and several were ecstatic. 30 min later, the scene could be completely different without any apparent reason.

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RE: Critical Review of a recently published discovery that RNA can induce an epigenetic engram (memory)

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