It is important to recognize that depression is not the problem in and of itself; it is a response or reaction to something else. For that reason, Scripture says almost nothing about depression per se. However, it has much to say about the root causes of depression. The Bible teaches that depression is not caused by the circumstances of our lives, but rather by our unbiblical reactions to those circumstances (with the exception of certain physical problems and brain disorders which we will deal with in a moment.