Well what is the most significant thing? The Univers isnt it? And we actualy are made of the same stuff. Like small version of the greatest thing possible. In scales of 7.5 x 1.000.000.000.000.000.000 its hard to thing about yourself as special if you are just have some guinness world record or you are a president of USA or you are a new Mozart. The only thing in this scales what matters IMHO is how can you relate yourself to something so magnificent like the Univers. And it comes out we can do it! And thats what makes you special.