Cavani begins his football career at the Danubio Fútbol Club. After two years in Montevideo and a title of Uruguay champion, Cavani joins Europe and the Italian club of US Palermo. Cavani is then loaned to SSC Naples in 2010, before being definitively bought by this club, for the sum of 17 million euros. Author of 28 goals in all competitions in his first two seasons, he finished top scorer in the Italian championship in the 2012-2013 season with 29 goals.