"Take away meaning en masse and my prediction is, many will struggle to find a center"
You only have to look at what happened to the Aboriginal people in Australia, who practiced walkabout and dreamtime, for 60,000 years, across land that was owned by nobody, until we came along and ruined it for them.
The meaning in their lives evaporating as the last aboriginal came in from walkabout, alcoholism and drug use and depression ravaged their communities.
This is a possible future for everybody who doesn't feel useful or have meaning in their lives. I suspect a Matrix will be created for humans to live fantasy lives of usefulness, and that will be a drug most people will never unplug from.
I'm probably too old to ever live in that world, but I worry for future generations. :(
This was engineered... but yes, they were destroyed.
@Markkujantunen mentioned the same and I agree.
I think I am borderline in age but, my condition means I am unlikely to see it.