Yes it is hard to be comprehensive but in a post about nucleases, someone who doesn't know what a nuclease might think of only the types you mentioned. So something like "What is a nuclease?" A nuclease is an enzyme that cuts nucleic acid (DNA or RNA) and scientist can direct nucleases to cut at specific sequences to edit genomes....(then mention the 3 as in your post). I just felt that there is so much history in the discovery of restriction enzymes that your post should have mentioned these very important nucleases. The Nobel Prize in Physiology or Medicine 1978 was awarded to Werner Arber, Daniel Nathans and Hamilton O. Smith for the discovery of restriction enzymes and their application in molecular biology.