Ketogenic Diets for Bipolar Disorder - Two Clinical Cases

in #research7 years ago

Ketosis for Type 2 Bipolar - [2 Clinical Cases].png


Last week I read a clinical report of two women using prolonged ketosis for managing their Type 2 Bipolar Disorder symptoms. This is a clinical report, and not a randomized double blind trial and it should be taken as such. Also, n=2 is a very small sample size.

However, this clinical report and countless anecdotal reports from people all over the world should somehow spark the interest of using dietary alterations for such conditions. The authors of the report suggest that the underlying mechanism of the success of these women with ketosis might be the acidification of plasma and the lowering of intracellular sodium and calcium - which are often the therapeutic targets of prescription drugs.

In short:

  • n=2, one women 69-year old, another 30-year old
  • maintained ketosis for, at least, 2, respectively 3 years
  • they might have maintained ketosis even after the publication of the report
  • they tracked urine ketones almost daily
  • they experienced no side effects.

Yes, these seem to be remarkable results. The authors however are careful to mention that ketogenic diets (if not formulated well) can lead to a whole host of negative side effects. They also discuss how they might have counteracted these side effects, the focus being on renal health. They conclude by saying that:

“At minimum, these patients’ experience suggests that a ketogenic diet, diligently pursued, can act as a mood stabilizer in patients with type II bipolar disorder.” [source]

If you're interested, you could read the full study here or read a lengthier review that I wrote on my personal blog about it:

Ketogenic Diets for Bipolar Disorder - Two Clinical Cases


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Cristi Vlad Self-Experimenter and Author

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This is wonderful news! Of course the extremely small sample size means no real scientist will take it at face value on its own (and rightfully so), but I can't help getting excited when I hear of all the wonderful things keto is doing for people.

It seems that it is gaining popularity this past year. I hope the trend continues.

It's been gaining popularity over the past few years.

Ah, so I didn't beat the trend, I was a part of it? Oh well. :)

Sometimes even tuning down the symptoms can be of the great help, still, the whole solution is I guess out of the reach because we know little about the brain.
It could be of the great help if the people could invest in similar studies, and not paying for some batshit crazy stuff nobody has any use off...

good point!

ok thats something about hidden science that normal people could not understand with a first read....
I think if there is any easy way or some videos can help them to understand.
I think if you continued on it........ Then it will be a great help for those people like me.

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