The impairment of chemical balance in your brain is important in the formation of this disease. The synapses between the neurons of the serotonin and noradrenaline in the brain are reduced in the given space. This decrease leads to the appearance of depressive symptoms. This decrease, which is sometimes spontaneous, sometimes occurs after some compelling life events. Past traumas, losses, sadness and difficulties, still ongoing problems, emerging coercive life events, low educational level, poverty can also cause depression.. @slimanepro @abigail-dantes