Highly fatal mycosis---> Mucormycosis

*Mucormycosis* is a rapidly evolving invasive fungal infection that preferentially affects immunocompromised patients and causes high morbidity and mortality. It is due to tissue invasion by different fungi of the Mucorales family, the most frequent belong to the genus Rhizopus, Rhizomucor, Mucor and Absidia.

The human species has a very effective natural immunity against Mucorales, so Mucormycosis occurs almost exclusively in patients with serious underlying diseases (transplant recipients, those under treatment with steroids or chemotherapy, HIV +, malnourished.) Despite this, it is the third cause of invasive fungal infection after candidiasis and aspergillosis, with an estimated frequency of 1.7 cases per million inhabitants per year.

This mycosis has a mortality that ranges between 10% and 70%. Its treatment is based on several phases or principles, where the most important are early diagnosis and rapid surgical debridement of injuries. Of course this goes hand in hand with antifungal treatment plus the elimination of predisposing factors (glucocorticoids, acidosis.)

reference sources
Medicina Interna Farreras-Rozman
 
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