Not a fan of it on the river. It's difficult to balance multiple betsizes, and having one of those betsizes as minimum on the river is not a great idea. It's a better idea on the turn to occasionally have small bets OOP to "set the price" yourself, rather than c/c a larger bet.

I would concentrate on having the proper ranges in standard betsizes first then start working with having multiple betsizes and trying to balance those ranges. It's usually pretty easy to exploit weak players with different strategies, but I wouldn't incorporate the min river bet. Small river bets are often necessary though, especially in spots where your range is incredibly strong and it's obvious.