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This kind of matrix is mainly used to experimental design and parameter optimization process. The orthogonal hypercube is similar to the orthogonal Latin hypercube in some literature. For typical literature, please refer to
C.D.Lin, D.Bingham, R.R.Sitter and B.Tang, A new and flexible method for constructing designs for computer experiments, The Annals of Statistics, Vol. 38, No.3, 1460–1477, (2010) and CDLin , New developments in designs for computer experiments and physical experiments. Ph.D. thesis, Simon Fraser Univ. (2008).

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