Vaccines as a trigger for early-childhood febrile seizures

By Erin Elizabeth

(Editor’s Note: We are so happy that the World Mercury Project continues to ask us to share their research with you. They truly care about the health and well-being of our children. Please educate yourself and as always, feel free to share this story with everyone you know.)
By the World Mercury Project Team

Febrile seizures (also called febrile convulsions) occur in young children in conjunction with fever and are the most common type of childhood seizure. Somewhere between two and five percent of American children will have at least one febrile seizure by age five, and anywhere from 23% to 43% of those will experience a recurrence.

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The incidence of both initial and recurrent febrile seizures is highest in children aged 14-18 months—which happens to be the same developmentally critical time period when young children receive up to nine vaccines for 13 different diseases. A sizeable body of evidence indicates that this synchronous timing is no coincidence, and that vaccines are risk factors for febrile seizures.

Not necessarily benign
In the past, child health experts regarded febrile seizures as mostly benign, but this relaxed attitude is now undergoing reconsideration as atypical “febrile seizure syndromes” become more common. In a study reported in the Annals of Neurology, almost one-fifth (18%) of children who experienced their first febrile seizure had prolonged seizures lasting, on average, 40 minutes. These more complex febrile seizures, when prolonged and/or recurrent, greatly increase the risk of subsequent neurological disorders.

In animal models, investigators have observed long-lasting abnormalities in the cortex and hippocampus of adult animals that experienced complex febrile seizures during early developmental stages. Research in humans has pointed to increased risk for Tourette syndrome and developmental delays following some types of febrile seizures. Studies also have linked a form of prolonged seizure called febrile status epilepticus (5% to 9% of all febrile seizures) to subsequent temporal lobe epilepsy and hippocampal sclerosis.

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