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The printing of high denomination notes is not a cause of inflation it is more the consequences. The main cause of inflation is the creation of base money, MB as it is called by the economist.
Thanks for commenting.

I always thought the main cause of inflation was the interest rate being paid for the note itself. The interest never exist and cannot ever exist under the current system.

Interesting question? They would not devalue any more than the lower denomination. However they might not be honored as the Federal Reserve is a criminal organization. lol