Paracetamol

one of the most safest drugs

act as analgesic and antipyretic

has weak anti-inflammatory effect

it is metabolized in liver by glutathion so , should not be given to acute or chronic liver patients.

N-acetyl-p-benzoquinone imine (NAPQI) is the substace which is responsible for toxicity.

Toxicity increases with other drugs like anti seizures (carbamazibine,phenytoin)

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