Non-specific inflammation of the digestive system, which can affect any part of it, from the oral cavity to the rectum, is diagnosed as Crohn's disease (IBD).
The inflammation that develops there is chronic and has periods of flare-up and alleviation of the disease. It causes diarrhea, bothersome abdominal pain, fatigue, and weight loss and malnutrition. Often ulcerations and nodules form on the intestinal mucosa. Due to the course of the disease, for example, adhesions appear on the intestinal wall, which ultimately lead to a narrowing of the intestinal lumen and a problem with the passage of intestinal contents through it.
CBD is a natural remedy used in the fight against IBD. Medicines currently available on the market for this disease are not completely safe, which we cannot say about marijuana. The body absorbs CBD very easily, without causing troublesome side effects. We can take them in many forms, from oil to capsules. Why is it worth doing this? The Crohn's and Colitis Foundation of America studies have documented a more effective action of cannabinoids in the treatment of Leśniewski and Crohn's disease than in the case of generally available therapies with other pharmaceuticals. This does not mean that the IBD has completely healed, but the symptoms have improved. CBD has an anti-inflammatory effect on our body, including the intestines, relieving inflammation in them. It soothes irritations of the intestines caused by defective intestinal motility, which often make too fast peristaltic movements. Stimulated CB1 receptors reduce the secretion of gastric juices, which also has a positive effect on the digestive process in this disease.
Scientists from the Department of Experimental Pharmacology, University of Naples in Italy, studying the effects of cannabinoids on inflammatory bowel disease, concluded that "CBD does indeed discover a new therapeutic strategy in the treatment of inflammatory bowel diseases", all thanks to the control of the neuroimmune axis.
Research conducted so far on intestinal diseases, including IBD, provides promising results. Not without significance, there are also testimonies of sick people who decided to use CBD therapy. The world of medicine is constantly researching the properties of cannabis, but currently available research already shows the effectiveness of treating inflammatory bowel diseases with one of its ingredients, i.e. CBD.
Cannabidiol reduces inflammation in the gut by controlling the neuroimmune axis. https://www.ncbi.nlm.nih.gov/pubmed/22163000
Cannabidiol, a safe and non-psychotropic component of the Cannabis sativa marijuana plant, protects in a mouse model of colitis. https://www.ncbi.nlm.nih.gov/pubmed/19690824
Effect of Delta-tetrahydrocannabinol and cannabidiol alone in association with in vitro damage, inflammation and motor dysfunction in rat colitis. https://www.ncbi.nlm.nih.gov/pubmed/20590574
Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice. https://www.ncbi.nlm.nih.gov/pubmed/22414698
Endocannabinoids and the gastrointestinal tract. https://www.ncbi.nlm.nih.gov/pubmed/16751708