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RE: Free Cannabis Oil for Cancer Patients -- My Plan/W.I.P
True, limonene can be considered a solvent and is 100% safe to use.
Co2 Super or Sub critical is the best though.
Though there is no study stating that THC helps inhibit cancer cell growth.
High THC is recommended for cancer patients for a number of reasons, though it is not to aid in destroying tumors or inhibit cancer cell growth.
First, let me say that I think your intentions are good in trying to help people. I also think that we now have better technology for extracting cannabinoids then we did 15 years ago, when Rick Simpson went public.
Rick's first recommendation is to use 99.9% isopropyl alcohol as the solvent or as a second option, an overproof alcohol (Everclear) as a solvent. He recommends naptha as a solvent if it's the only solvent that a person can get in their area to make the oil.
By far, a Co2 extraction is the better way to go for someone who is sick and dying.
My concern is that CBD sourced from industrial hemp plants is not strong enough to stop the progression of cancer cells on its own.
To do this, you need activated THC that has been decarboxylated into 9-THC and then metabolized through the liver to form the molecule 11-THC. This means that 9-THC must be eaten. Smoking or vapourizing will not lead to the production of 11-THC.
11-THC will bind to both CB1 and CB2 receptors in the body and CBD only binds to the CB2 receptors.
When 11-THC binds to a cancer cell it raises the cell's ceramide level which doesn't allow the mitocondria (or energy powerhouse of the cell) to work. In addition, 11- THC will also disrupt the calcium metabolism of the cancer cell. This 2-stage process is unique to THC.
CBD, from cannabis indica, will also disrupt the calcium metabolism of the cancer cell and it also is responsible for what's known as the "Caspase Cascade" which breaks down the protein and pepetide chains within the cell, causing cancer cell death.
These processes involve both THC and CBD and will kill cancer cells.
My understanding is that the CBD must be derived from a cannabis indica plant strain and that it becomes more beneficial when it works synergistically with 11-THC.
Here's a link to a Biochemist's take on how these processes work:
https://patients4medicalmarijuana.wordpress.com/2015/02/19/dennis-hill-how-cannabinoids-kill-cancer/
With cancer it always feels like a race against time, once the autoimmune disease is discovered.
I would want to take advantage of both THC and CBD sourced from cannabis indica, if I had cancer.
I would not rely on industrial hemp, alone.
I would encourage anyone who may read this comment to research it for themselves.
Thank you! The biggest reward is the immensely emotional conversions I get to have with patients once they're "out of the woods".
Yes - 100% Yes! Do as much research as you possibly can! Fill your brain with as much knowledge as you can. If along the way, one decides that they'd like to pursue CBD products. We will be here. :)
Isopropyl is never good to use. Right on Section 3 of the MSDS you can read:
"DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Development toxin [POSSIBLE].
The substance may be toxic to kidneys, liver, skin, central nervous system (CNS). Repeated or prolonged exposure to the
substance can produce target organs damage."
Although the indica strains typically contain a higher quantity of phyto-chemicals that are considered to be beneficial, once isolated from the plant in high quantities - it makes no difference which strain it came from.
Yes, you're correct - decarboxylation is a big step, for "activating" THC-A, into the delta 9 THC. Once activated it drops that acidic molecule, so tetrahydrocannibidolic-acid turns into delta 9 tetrahydrocannibinol. Once delta 9 THC has been eaten, and passes through the liver it metabolizes into 11 hydroxy tetrahydrocannibinol. You didn't miss a beat on that!
Though these cannabinoids are analgesic and antiemetic, they only aid slightly in the process of killing cancer cells.
If patients are registered license holders in Canada, we can give you access to real RSO, with all the THC benefits. Though with THC prohibition in place, (in most places), we can not in good conscious instruct anyone to risk their liberty and break laws. No matter how much we disagree with those laws.