As a relatively new participant to the whole crypto workl I am sharing some of my feedback in dealing with some of the Top 5
Coinbase - if you are going to trade regularly I would advise to use GDAX ,its trading platform , when using GDAX , you eliminate the comission fee by making the trade yourself, you can also use the Stop Loss and Limit trade function . In the Coinbase platform you cannot use these.

Bitfinex, you need to deposit an initial $10K - this is probhitive for a small trader.

Kraken - it has disabled it Stop Loss function. This is not a smart move for those who want to protect their investment