Researchers in Brazil found opioid peptides in coffee over a year ago. Biotechnology Resources Division and the UnB successfully "identified previously unknown fragments of protein - peptides - in coffee that have an effect similar to morphine, in other words they have an analgesic and sedative activity."

Those peptides, the note said, "have a positive differential: their effects last longer in experiments with laboratory mice."

The two institutions applied for patents to Brazilian regulators for the seven "opioid peptides" identified in the study.

Both mitragynine and 7-hydroxymitragynine are structurally different from any opioid we have today. In fact, there is a much greater separation of side effects due to the fact that these two alkaloids do not recruit Beta Arrestin, which means it's impossible to overdose on and does not cause respiratory depression.

Many substances have binding affinity for opioid receptors, such as sugar. In fact, people often get addicted to sugar and/or food. Those people abuse food because of the effect it has on their brain reward system. There's a myth that addiction is a result of a given drug or chemical when in reality addiction is a symptom of a deeper issue. Whether a person abuses kratom, sugar, food, alcohol or nicotine the problem is the relationship the person has with the substance. Plenty of people, myself included, take kratom to manage chronic pain because there just aren't any other options for us. Chronic Pain is already under treated as it is because the CDC and DEA together have tied the hands of doctors. Why? Because someone took pills that didn't belong to them and overdosed on them. So the Chronic Pain patient gets to suffer. If you look at the rate of addiction for the entire planet, it's about .05% according to my textbook on Chemical Dependency. What that means is that the other 95% of the human population does not have a Substance Use Disorder. We legislate for the minority and this should not be the case.

SOURCE: http://www.ibtimes.co.uk/painkiller-discovered-coffee-that-stronger-morphine-lasts-longer-1485238