MOLECULAR MONSTER OFF DIFFICULTY

in #indonesia7 years ago (edited)

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The moster was named Corynebacterium diphtheriae. He is ferocious, brutal, and is killing Indonesian children mercilessly. The toxin it produces is a molecular machine capable of killing cells by inhibiting protein synthesis. One molecule alone is enough to kill one cell. Not to mention the ability to penetrate the various types of human tissue, ranging from tonsils, oral mucosa, skin, even the membranes in the heart. But did you know that actually Corynebacterium diphtheria originally did not have such a lethal ability?
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Naturally, Corynebacterium diphtheria has no genes to produce the toxin. The ability is obtained through symbiosis mutualism with a kind of virus which then leads to a genetic mutation of insertion of toxin genes into copies of the genome of the Corynebacterium diphtheriae. Imagine Corynebacterium diphtheriae as a collection of stupid soldiers who accidentally discovered sophisticated weaponry and then made a massive invasion into the human body. Knowledge of the genetic properties of these germs is the basis that the only best, cheapest, and best way to eradicate diphtheria is vaccination. Why is that?

Visrus, bombs or Germs that get their toxic properties from genetic mutations in the form of insertion due to viruses generally do not have the ability to modify the toxic properties. In other words, if we succeed in paralyzing their main weapon, the toxin, then they will lose the ability to cause disease and strains that are toxic will eventually become extinct. That's exactly what diphtheria vaccine does. Diphtheria vaccine in the form of toxoids, ie toxins that have been disabled. The process of making it simple, you just need to add aldehyde groups to the toxin. When administered into your body, the immune system will immediately catch it and create a strong memory of the toxin.

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If at any time Corynebacterium diphtheriae producing toxins enters the body of your child who has been given the vaccine, the immune system will instantly recognize it and eradicate them without mercy. Conversely, when your child is an antivaxin whose body has no memory of a diphtheria toxin, your child's immune system will be late in exterminating, and the damage will be too extensive to handle. Your child will first experience symptoms like a normal sore throat. It's just that there is a white membrane that is increasingly widespread in the mouth of your child, causing pain that makes your child lazy to eat and increasingly weak. Your tonsils and lymph nodes will enlarge so you begin to have difficulty breathing. And when the toxin has reached the heart, there is a 85% chance your child will die.

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Family health is the dream of all humans

Photo above I am mengabil from one public hospital in Indonesia precisely in Aceh.

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