You will not be able to smoke them out. You have to open the wall and remove the comb and bees. A big job. The odds are low that they would nest again close. Smoking simulates a forest fire. If they do decide to leave from smoking they will likely get as far away as they can. The brood and bees left behind will raise a new queen. And you start all over again. To save the bees you have to remove them. Not an impossible job but one with a lot of work and tricks involved. Like getting their comb into frames. There are many strategies to consider based on experience, available equipment cost etc. I have done this on many occasions over the years. I suggest you find an experienced beekeeper that can help you with the process and aid you in the long learning curve to looking after them. My https://beemaster.ca site and @beemasterca are dedicated to helping beekeepers becomeing beekeepers.