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Yes with the O group there is the Rhesus factor
Since the O group lack the antigens on it’s surface the anti Rh serum D which is used for Rhesus is also use to determine the O group which makes it Rhesus positive or negative in case of agglutination or not respectively

The O group as a whole is the universal group both positive and negative the only advantage with O negative is that it can be used as a first line of emergency without screening.
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