A practical example of asymmetric bet is when TSLA was $200-220 back in August. A $2500 ($10x250) bet on options from 6 month afar could earn a heck of $62.5K ($250x250). It was very unlikely that TSLA would trade below $200 in that time period, therefore, there is very low risk of losing $2500 altogether.
One of my friends was early in on Atlassian, and that has got a few pumps along its short journey and looks like it isn't slowing down soon.