Killers Rising: Candida Auris

in STEMGeeks6 years ago

candida.jpg

         That PSA has been up for months in the department. And yet, I still have not come across a culture with possible Candida auris. For those of you who are unfamiliar with the organism, it is one of the latest worries under the CDC watchful eyes. Why? Because this yeast is resistant to multiple drugs used in fungal infections. On top of that, it is not too difficult to misidentify it.

         A brief history shows that it was first described in 2009 and caught attention in the medical field in 2016. For more general information, please visit the CDC's page:

https://www.cdc.gov/fungal/candida-auris/candida-auris-qanda.html

         In essence, it's like any other Candida infection, but deadlier. From the CDC's general information, it would appear to be a nosocomial infection. When you combine multi-drug resistance and immunocpromised patients, bad things happen. It is a practical death sentence.

         As a laboratory professional, I am told that it is easy to misidentify this organism. Here's a chart from the CDC website:

candida2.png

         From that, I can understand why Candida haemulonii appeared on the PSA. It is actually the closest related species to our culprit. As for the name Candida parapsilosis, it is not an uncommon find at work, but it does make you wonder if it's C. auris. The good news is, I have not seen the pink yeast colonies on CHROMagar described on the website.

         So, what is the most reliable identification method according to the medical authorities? It turns out the MALDI-TOF is our best friend in this case. For a while, I thought that our department might have been missing C. auris infections.

candida3.png

         Our lab uses the Bruker Biotyper. Since this year's switch to the BD Kiestra automation, all our software, hardware, etc. had to be up to date. Part of me feel more secure knowing that we are using the latest technology in healthcare.

         The real question is, has there been any cases of Candida auris infection in Utah? Well, as of March of this year (2019), there was no reported cases according to the State.

http://health.utah.gov/epi/reporting/AR_lab_guidance_letter.pdf

         Does that mean it won't happen? I don't know and I doubt it. Should you worry about this particular organism? Most likely because the nature of this beast seems closer to opportunistic infections.

         It will be interesting to see if new drugs and treatments will come about to combat this rising killer.

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I don't know how doctors are with antibiotics over there, but here they seem to be more careful prescribing it. Which is a good thing, even though I've visited the doctor 3x for my daughter, while I longed for a cure lol...

So many people keep getting antibiotics and if you catch a candida like this, like you said, you may have signed your death sentence. My boyfriend also worked as a laboratory professional before he decided that this wasn't for him.

Comes in handy, especially when mold is found in the apartment (again, like last winter) he knows how to deal with that lol..

 6 years ago 

Well, antibiotics don’t work on fungi anyhow.

I didn't mean that lol.. :)

They covered just about everything except what symptoms you could expect yourself to be having if you visited a hospital where this was on the surface of something and you contacted it.

 6 years ago 

Most organisms are only dangerous once they are inside you.

You may want to wash them off still though.

You may want to wash them off still though.

Thanks Sherlock.

 6 years ago 

Symptoms suggest you have already developed disease.

This is more of a concern for immunocompromised patients than a healthy one.

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