This is usually caused from a magnesium deficiency. I know because I went through this for a long time. It started after I had a hyterectomy when I was 35 due to the shock of hormonal imbalance. Once I started learning about the imbalance of magnesium and the symptoms I figured it out. I consulted with a naturopath doctor. There are many ways to get magnesium and also different kinds of magnesium. Epsom Salts is magnesium sulfate and can relief symptoms temporarily. Magnesium Chloride stays in the body for longer periods of time so the body can use it. You can find Magnesium Chloride in some health food supply stores and I believe Amazon sells it as well. If you live near the ocean, go get in the water. That is the largest form of Magnesium we have on the planet. Magnesium usually comes in an oil form. It can be applied straight to the legs or bottom of the feet. The relief for me was immediate and I still use it. I'm not a doctor but I do know what worked for me. I hope this helps. Good luck on your journey of healing.