DRUG DISCOVERY(PART5:metformine) im pharmacy student and i want to make some post about my job content is about drug and discovery of drug

is a principle biguanide antihyperglycemic agent used agent, represents a mainstay of today's therapy in the treatment of non-insulin-dependent diabetes mellitus and shows significant effectiveness in decreasing the risk of disease development.
Type 2 diabetes is a serious disease, and it’s on the increase. The search for a treatment is a story
that traverses the world and touches on the treatment of several other diseases.
Drug of a plant origin:Galega officinalis (also known by many other names as goat's rue, false indigo, professor-weed, French lilac, ) is a summer-flowering perennial herb with white, blue or purple flowers found in most hot regions.
The history of clinical usage:clinical experience with galegine sulphate was mentioned Muller and Reinwein in 1927. They experimented with a 109 mg of galegine sulphate, after which blood glucose levels were followed for 25 hours.

Metformin discovered in 1922. French physician Jean Sterne began study in bodyin the 1950. It was introduced as a medication in France in 1957 and the United States in 1995. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.
structure:

metformin is used to improve blood sugar control in people with type 2 diabetes. but this medicine is not for treating type 1 diabetes.
Before taking this :To make sure metformin is safe for you, tell your doctor if you have:
kidney disease
liver disease
a history of heart disease or recent heart attack
if you have recently taken chlorpropamide or
if you are over 80 years old and have not recently had your kidney function checked.
metformin synthsis :



Antidiabetic II drug metformin in plants: uptake and translocation to edible parts of cereals, oily seeds, beans, tomato, squash, carrots, and potatoes.

is an herbaceous plant in the Faboideae subfamily.