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RE: Debunk-Tuesday – Cannabis Cures Cancer

in #health • 6 years ago

I just had a quick look at the paper [1]. In the background I came across the sentence

We also analyzed the expression of cannabinoid targets in a series of 87 human breast tumors. cannabinoid targets in a series of 87 human breast tumors.

What does she mean with this?

6 years ago in #health by
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     6 years ago (edited)

    According to the study they used tissue samples from 87 human tumors (so no in vivo on actual humans here) to see how they would respond to the usage of cannabinoids:

    We performed an immunohistochemical analysis of CB1 and CB2 receptors in 87 grade 3 invasive breast ductal carcinomas and 6 non-tumoral mammary samples by tissue microarrays. CB1 immunoreactivity was detected in only 14% of the tumors (12/87), and no correlation was found between this receptor expression and ErbB2 expression (p = 0.198, Fig. ​Fig.1).1). Conversely, CB2 receptor staining was evident in 72% of the carcinomas (63/87) and it was significantly associated with ErbB2 expression, since it was observed in 91% of the ErbB2-positive tumors (21/23, p = 0.018, Fig. ​Fig.1).1).

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