Autosomal dominant inheritance pattern

Autosomal dominant inheritance pattern

In an autosomal dominant disorder, the mutated gene is a dominant gene located on one of the autosomal chromosome. A person with only one mutated gene has this type of disorder. A person with an autosomal dominant disorder has a 50% risk of having an affected child with one mutated gene.

Examples of autosomal dominant disorders include neurofibromatosis type 1, Marfan syndrome, Peutz-Jeghers syndrome, Poydatyly, Familial hypercholesterolemia, Gardner's syndrome, Huntington's disease, Von Hippel-Lindau disease, and multiple endocrine neoplasia.