Scientists from the University of New South Wales (Australia) and Harvard School of Medicine (USA) have developed a new way to combat muscle aging with a combined preparation of two chemical compounds. The method simulates the effect of physical exercises. With age, the flow of blood to the tissues and organs is reduced, which worsens their functioning. It is shown that the level of the oxidized form of nicotinamide adenine dinucleotide (NAD) decreases thereby decreasing the metabolism of the cell. However, the introduction of nicotinamide mononucleotide (NMN) as well as hydrogen sulphide into the mice allowed to increase physical endurance by 60 percent in both young and old rodents.

The results of the study showed that 32-month-old animals who received combination therapy for four weeks were twice as hardy animals in the control group. The indices of those mice, in whose organism the level of NMN alone increased, improved 1.6 times. According to the researchers, this is due to the fact that both compounds stimulate the activity of the SIRT1 protein involved in the formation of blood vessels.