Drug metabolism in your body!!!

in #healt6 years ago (edited)

The metabolism of drugs or drugs includes a set of chemical modifications that suffer the drugs in the body by the action of different enzymes, can be metabolized by reactions of oxidation, reduction, hydrolysis, hydration, verb conjugation, condensation or isomerization, with the objective of facilitating their excretion.

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An inactive substance or weakly active which gives rise to an active metabolite is called a prodrug, especially when it has been designed to address more effectively the active form to your destination.

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In many cases, the drug metabolism includes two phases. In the phase I reactions form, modify, or delete (oxidation, reduction or hydrolysis) a functional group; these reactions are not the synthetic character. Phase II reactions consist in the conjugation with endogenous substances (e.g., glucuronic acid, sulphate, glycine); these reactions are synthetic in nature. The metabolites that are formed in the synthetic reactions are more polar and therefore easier to excrete via the kidney (in the urine) or liver (in the bile) than they do in synthetic reactions. Some drugs only experience reactions of phase I or phase II; therefore, the numbering of the phases is a functional classification, not sequential.

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Phase I reactions

tend to be oxidation, reduction or hydrolysis which introduce into the structure a group reactive it chemically more active, change of activity or inactivation.

Phase II reactions

tend to be conjugation reactions that inactivate the drug. Usually act on the body reagent introduced in Phase I.

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To my community of Steem It a big hug and I hope that this topic is of interest to you.

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Hola @marier, te comento que el tag spanish se utiliza para contenidos que estén escritos en español parcial o totalmente. También te recomiendo añadir las fuentes de las imágenes que no sean de tu propiedad. Esto puedes hacerlo debajo de cada imagen o al final de la publicación mencionándolas adecuadamente.

Saludos!

Hola Amiga, muchas gracias por tus consejos. Lo tendré presente para próximos post, tienes toda la razón. Sigueme y te sigo. Podrías recomendarme algún sitio web para mejorar las publicaciones en cuanto al estilo de la letra y hacer mejores diseños?

Hola @marier puedes pasarte por mi perfil. Allí hay una publicación que puede servirte.

Saludos!

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