when will it get better for her ......Mental instability

I have seen my sister go on a downward spiral for about 30 years , over time it has gotten worse, she is about to be 53 years old and refuses mental help. She was diagnosed many years ago and they had made her a medical lab rat , giving her every type of drug and over time she began to become more paranoid about everything and everyone!. She thinks the voices she hears in her head are real , and acknowledge them as if they were real and in front of her?
How and when will she get help. she listens to no-one . She carrries around a 3 inch blade now as she fears people hurting her, I don't know what or how to help her.Its worse now , because she lives in her car and rarely eats , Its been 15 below but yet she stays in her car. she had threatened my father with it and that is why my parents asked her to leave their home.Please if anyone can tell me my options i would really appreciate it!!

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